Doxy PEP

Sexual Health

Mfg : Chartwell
In-Stock

Doxy PEP 100mg

Post-Exposure STI Prevention DoxyPEP is a CDC-recommended prescription antibiotic taken within 72 hours after sex to reduce the risk of syphilis, chlamydia, and gonorrhea.

Proven Effective Clinical trials show up to 88% reduction in chlamydia and syphilis, and 45-55% reduction in gonorrhea

CDC-Recommended Recommended for gay, bisexual, and other MSM and transgender women with a bacterial STI in the last 12 months

Simple Dosing One 200 mg dose taken within 24-72 hours after oral, anal, or vaginal sex

Prescription Required Requires medical evaluation and regular STI screening every 3-6 months as part of a comprehensive sexual health approach

Disclaimer: The FDA may not have evaluated this product for safety, effectiveness, or quality.
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Real Stories, Real Results

What Is DoxyPEP?

DoxyPEP—short for Doxycycline Post-Exposure Prophylaxis—is a proven, prescription-based strategy that uses the antibiotic doxycycline to prevent bacterial sexually transmitted infections after sexual exposure. When taken as directed within 72 hours after condomless sex, it can dramatically reduce the risk of acquiring syphilis, chlamydia, and gonorrhea.

How DoxyPEP Works

Doxycycline is an antibiotic that stops the growth of bacteria that cause STIs. When taken shortly after exposure, it prevents the bacteria from establishing an infection. Clinical trials show that DoxyPEP reduces the risk of chlamydia and syphilis by up to 80% and provides moderate protection against gonorrhea.

Who Should Consider DoxyPEP?

The CDC recommends that healthcare providers discuss DoxyPEP with:

Gay, bisexual, and other men who have sex with men (MSM) and transgender women who have had a bacterial STI (syphilis, chlamydia, or gonorrhea) in the past 12 months.

Individuals who engage in sexual activities known to pose an increased risk of infection.

Product Specifications

Product Name: DoxyPEP Preventative

Category: STI Prevention & Sexual Health

Active Ingredient: Doxycycline

Dose per Use: 200 mg (two 100 mg tablets)

Form: Oral Tablet

Optimal Timing: Within 24 hours, no later than 72 hours after sex

Indication: Prevention of bacterial STIs

Prescribing Service: Available through licensed healthcare providers

How to Take DoxyPEP

Timing: Take 200 mg of doxycycline as soon as possible, within 72 hours after oral, anal, or vaginal sex.

Dosing: Do not take more than one dose (200 mg) in a 24-hour period, regardless of how many times you have sex.

Administration: Take with at least 8 ounces of water and food to reduce side effects. Do not lie down for one hour after taking doxycycline to prevent esophageal irritation.

Avoid: Do not take doxycycline within two hours of dairy products, antacids, or supplements containing iron, calcium, or magnesium, as these can interfere with absorption.

Proven Effectiveness

Large clinical trials have demonstrated the effectiveness of DoxyPEP:

Chlamydia: Up to 88% reduction in risk

Syphilis: Up to 87% reduction in risk

Gonorrhea: 45% to 55% reduction in risk

Important Safety Information

Does Not Prevent Viral STIs: DoxyPEP does not protect against HIV, herpes, HPV, hepatitis, or mpox.

Not a Treatment: This is a preventative measure, not a treatment for active STIs. Regular testing every 3-6 months is required.

Side Effects: May include nausea, upset stomach, sun sensitivity, and esophageal irritation. These can be minimized by taking with food and water.

Antibiotic Resistance: Researchers continue to study the long-term impact of DoxyPEP on antimicrobial resistance. Use only as directed.

Follow-Up Care

Patients prescribed DoxyPEP should continue regular STI and HIV screening every 3-6 months. At these visits, healthcare providers will reassess the ongoing need for DoxyPEP and provide additional doses based on sexual frequency.